BDBM50322742 CHEMBL1173694::N-(2-(1H-benzo[d]imidazol-2-yl)ethyl)-2-(2-bromophenoxy)acetamide::N-[2-(1H-benzimidazol-2-yl)ethyl]-2-(2-bromophenoxy)acetamide

SMILES Brc1ccccc1OCC(=O)NCCc1nc2ccccc2[nH]1

InChI Key InChIKey=XWFRNTHGPRGCNS-UHFFFAOYSA-N

Data  2 KI  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50322742   

TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50322742(CHEMBL1173694 | N-(2-(1H-benzo[d]imidazol-2-yl)eth...)
Affinity DataKi:  2.00E+3nMAssay Description:Binding affinity to Trypanosoma cruzi Cruzain assessed as inhibition constantMore data for this Ligand-Target Pair
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50322742(CHEMBL1173694 | N-(2-(1H-benzo[d]imidazol-2-yl)eth...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi cruzain assessed as Z-Phe-Arg-aminomethylcoumarin cleavage by competetive binding assayMore data for this Ligand-Target Pair
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50322742(CHEMBL1173694 | N-(2-(1H-benzo[d]imidazol-2-yl)eth...)
Affinity DataIC50:  800nMAssay Description:Inhibition of Trypanosoma cruzi CruzainMore data for this Ligand-Target Pair
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50322742(CHEMBL1173694 | N-(2-(1H-benzo[d]imidazol-2-yl)eth...)
Affinity DataIC50:  800nMAssay Description:Inhibition of Trypanosoma cruzi cruzaine expressed in Escherichia coli SG13009 using Z-FR-AMC as substrate after 5 minsMore data for this Ligand-Target Pair
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50322742(CHEMBL1173694 | N-(2-(1H-benzo[d]imidazol-2-yl)eth...)
Affinity DataIC50:  800nMAssay Description:Inhibition of Trypanosoma cruzi CruzainMore data for this Ligand-Target Pair